Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction in SH-SY5Y Cells via Inhibition of Mitochondrial Oxidation and Up-Regulation of DJ-1 Protein Expression

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic (DA) neurons at the substantia nigra. Mitochondrial dysfunction is involved in the mechanism of cell damage in Parkinson’s disease (PD). 6-Hydroxydopamine (6-OHDA) is a dopamine analog which sp...

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Main Authors: Yue-Hua Wang, Hai-Tao Yu, Xiao-Ping Pu, Guan-Hua Du
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2013-11-01
Colecção:Molecules
Assuntos:
baicalein
Parkinson’s disease
6-hydroxydopamine
SH-SY5Y cells
brain mitochondria
Acesso em linha:http://www.mdpi.com/1420-3049/18/12/14726
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