Synthetic Cathinones Induce Cell Death in Dopaminergic SH-SY5Y Cells via Stimulating Mitochondrial Dysfunction

Increasing reports of neurological and psychiatric complications due to psychostimulant synthetic cathinones (SCs) have recently raised public concern. However, the precise mechanism of SC toxicity is unclear. This paucity of understanding highlights the need to investigate the in-vitro toxicity and...

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Main Authors: Huey Sze Leong, Morgan Philp, Martin Simone, Paul Kenneth Witting, Shanlin Fu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
Colecção:International Journal of Molecular Sciences
Assuntos:
mitochondrial dysfunction
calcium dysregulation
apoptosis
synthetic cathinones
sh-sy5y
Acesso em linha:https://www.mdpi.com/1422-0067/21/4/1370
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