Release of membrane-bound vesicles and inhibition of tumor cell adhesion by the peptide Neopetrosiamide A.

Neopetrosiamide A (NeoA) is a 28-amino acid tricyclic peptide originally isolated from a marine sponge as a tumor cell invasion inhibitor whose mechanism of action is unknown.We show that NeoA reversibly inhibits tumor cell adhesion, disassembles focal adhesions in pre-attached cells, and decreases...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pamela Austin, Markus Heller, David E Williams, Lawrence P McIntosh, A Wayne Vogl, Leonard J Foster, Raymond J Andersen, Michel Roberge, Calvin D Roskelley
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2010-05-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC2877099?pdf=render
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge