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Release of membrane-bound vesicles and inhibition of tumor cell adhesion by the peptide Neopetrosiamide A.
Neopetrosiamide A (NeoA) is a 28-amino acid tricyclic peptide originally isolated from a marine sponge as a tumor cell invasion inhibitor whose mechanism of action is unknown.We show that NeoA reversibly inhibits tumor cell adhesion, disassembles focal adhesions in pre-attached cells, and decreases...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2010-05-01
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| Серии: | PLoS ONE |
| Online-ссылка: | http://europepmc.org/articles/PMC2877099?pdf=render |
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