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In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control

Summary: In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are involved in mitochondrial functions has not been investigated. Here, using wild-type β-actin +/+ and knockout (KO) β-actin −/− mouse e...

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Bibliographische Detailangaben
Hauptverfasser: Xin Xie, Tomas Venit, Nizar Drou, Piergiorgio Percipalle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018-05-01
Schriftenreihe:iScience
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2589004218300531
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