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In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control

In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are involved in mitochondrial functions has not been investigated. Here, using wild-type β-actin +/+ and knockout (KO) β-actin −/− mouse embryonic...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Xie, Xin, Venit, Tomas, Drou, Nizar, Percipalle, Piergiorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137402/
https://ncbi.nlm.nih.gov/pubmed/30428323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.021
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