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The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta
The human adaptive immune response enables the targeting of epitopes on pathogens with high specificity. Infection with a pathogen induces somatic hyper-mutation and B-cell selection processes that govern the shape and diversity of the antibody sequence landscape. To date, even the largest immunome...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis Group
2022-12-01
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| Serier: | mAbs |
| Fag: | |
| Online adgang: | https://www.tandfonline.com/doi/10.1080/19420862.2022.2068212 |
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