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The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta

The human adaptive immune response enables the targeting of epitopes on pathogens with high specificity. Infection with a pathogen induces somatic hyper-mutation and B-cell selection processes that govern the shape and diversity of the antibody sequence landscape. To date, even the largest immunome...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Samuel Schmitz, Emily A. Schmitz, James E. Crowe, Jens Meiler
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis Group 2022-12-01
श्रृंखला:mAbs
विषय:
ऑनलाइन पहुंच:https://www.tandfonline.com/doi/10.1080/19420862.2022.2068212
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