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Rosetta design with co-evolutionary information retains protein function

Computational protein design has the ambitious goal of crafting novel proteins that address challenges in biology and medicine. To overcome these challenges, the computational protein modeling suite Rosetta has been tailored to address various protein design tasks. Recently, statistical methods have...

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Publicat a:PLoS Comput Biol
Autors principals: Schmitz, Samuel, Ertelt, Moritz, Merkl, Rainer, Meiler, Jens
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815116/
https://ncbi.nlm.nih.gov/pubmed/33465067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008568
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