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PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

Abstract Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metastasis, and growth. Poly (ADP-ribose) polymerase (PAR...

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Main Authors: Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2022-05-01
Sraith:BMC Cancer
Ábhair:
Rochtain Ar Líne:https://doi.org/10.1186/s12885-022-09651-9
Clibeanna: Cuir Clib Leis
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