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The Mechanism of β2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish

Summary: Contemporary antigen presentation knowledge is based on the existence of a single β2m locus, and a classical MHC class I forms a complex with a peptide (i.e., pMHC-I) to trigger CTL immunity. However, two β2m loci have been found in diploid bony fish; the function of the two β2m molecules i...

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Autors principals: Zibin Li, Nianzhi Zhang, Lizhen Ma, Lijie Zhang, Geng Meng, Chun Xia
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020-05-01
Col·lecció:iScience
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589004220303047
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