Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progressionResearch in context

Background: Multiple Sclerosis (MS) is a chronic inflammatory disease and a leading cause of progressive neurological disability among young adults. DNA methylation, which intersects genes and environment to control cellular functions on a molecular level, may provide insights into MS pathogenesis....

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Main Authors: Ewoud Ewing, Lara Kular, Sunjay J. Fernandes, Nestoras Karathanasis, Vincenzo Lagani, Sabrina Ruhrmann, Ioannis Tsamardinos, Jesper Tegner, Fredrik Piehl, David Gomez-Cabrero, Maja Jagodic
Format: Artigo
Language:Inglês
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302816
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