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Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract
Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Limited
2015-01-01
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| Серии: | Journal of Ophthalmology |
| Online-ссылка: | http://dx.doi.org/10.1155/2015/579695 |
| Метки: |
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