Antibody-Drug Conjugates: The New Frontier of Chemotherapy

In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents to be used as one of the tools in personalized cancer medicine. ADCs are comprised of a drug with cytotoxic activity cross-linked to a monoclonal antibody, targeting antigens expressed at higher levels on tumor c...

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Detalhes bibliográficos
Main Authors: Sara Ponziani, Giulia Di Vittorio, Giuseppina Pitari, Anna Maria Cimini, Matteo Ardini, Roberta Gentile, Stefano Iacobelli, Gianluca Sala, Emily Capone, David J. Flavell, Rodolfo Ippoliti, Francesco Giansanti
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-07-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Mabs
Antibody-Drug Conjugate
cancer therapy
drug targeting
payload
cross-linking
Acesso em linha:https://www.mdpi.com/1422-0067/21/15/5510
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