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TOOme: A Novel Computational Framework to Infer Cancer Tissue-of-Origin by Integrating Both Gene Mutation and Expression
Metastatic cancers require further diagnosis to determine their primary tumor sites. However, the tissue-of-origin for around 5% tumors could not be identified by routine medical diagnosis according to a statistics in the United States. With the development of machine learning techniques and the acc...
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Frontiers Media S.A.
2020-05-01
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Serie: | Frontiers in Bioengineering and Biotechnology |
Soggetti: | |
Accesso online: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00394/full |
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