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TOOme: A Novel Computational Framework to Infer Cancer Tissue-of-Origin by Integrating Both Gene Mutation and Expression

Metastatic cancers require further diagnosis to determine their primary tumor sites. However, the tissue-of-origin for around 5% tumors could not be identified by routine medical diagnosis according to a statistics in the United States. With the development of machine learning techniques and the acc...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: He, Binsheng, Lang, Jidong, Wang, Bo, Liu, Xiaojun, Lu, Qingqing, He, Jianjun, Gao, Wei, Bing, Pingping, Tian, Geng, Yang, Jialiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248358/
https://ncbi.nlm.nih.gov/pubmed/32509741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00394
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