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A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans.

In Caenorhabditis elegans and Drosophila melanogaster, the aging of the soma is influenced by the germline. When germline-stem cells are removed, aging slows and lifespan is increased. The mechanism by which somatic tissues respond to loss of the germline is not well-understood. Surprisingly, we hav...

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Bibliographic Details
Main Authors: Arjumand Ghazi, Sivan Henis-Korenblit, Cynthia Kenyon
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2729384?pdf=render
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