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New Genes that Extend C. elegans’ Lifespan in Response to Reproductive Signals

In C. elegans and Drosophila, removing germline stem cells increases lifespan. In C. elegans, this lifespan extension requires DAF-16, a FOXO transcription factor and DAF-12, a nuclear hormone receptor. To better understand the regulatory relationships between DAF-16 and DAF-12, we used microarray a...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: McCormick, Mark, Chen, Kan, Ramaswamy, Priya, Kenyon, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342234/
https://ncbi.nlm.nih.gov/pubmed/22081913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00768.x
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