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DAMEfinder: a method to detect differential allele-specific methylation

Abstract Background DNA methylation is a highly studied epigenetic signature that is associated with regulation of gene expression, whereby genes with high levels of promoter methylation are generally repressed. Genomic imprinting occurs when one of the parental alleles is methylated, i.e., when the...

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Detalhes bibliográficos
Main Authors: Stephany Orjuela, Dania Machlab, Mirco Menigatti, Giancarlo Marra, Mark D. Robinson
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-06-01
Colecção:Epigenetics & Chromatin
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Acesso em linha:http://link.springer.com/article/10.1186/s13072-020-00346-8
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