Application of heteroduplex analysis for CALR mutation screening detection in patients with Ph-myeloproliferative neoplasms

Background. In accordance with the World health organization clinical guidelines, the analysis of somatic mutations in the CALR gene, as well as mutations in the JAK2 and MPL genes, are included in the list of criteria for the Ph-myeloproliferative neoplasms diagnosis.More than 50 different mutation...

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Main Authors: T. N. Subbotina, D. V. Kurochkin, I. E. Maslyukova, A. S. Khazieva, E. V. Vasiliev, M. A. Mikhalev, E. A. Dunaeva, K. O. Mironov
Formato: Artigo
Idioma:Russo
Publicado em: ABV-press 2021-06-01
Colecção:Onkogematologiâ
Assuntos:
ph-myeloproliferative neoplasm
calr
heteroduplex analysis
sanger sequencing
Acesso em linha:https://oncohematology.abvpress.ru/ongm/article/view/474
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