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Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy
ABSTRACT Aim: to analyze the effect of metformin on ammonia production derived from glutamine metabolism in vitro and in vivo. Methods: twenty male Wistar rats were studied for 28 days after a porto-caval anastomosis (n = 16) or a sham operation (n = 4). Porto-caval shunted animals were randomized...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
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| 叢編: | Revista Espanola de Enfermedades Digestivas |
| 主題: | |
| 在線閱讀: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082018000700004&lng=en&tlng=en |
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