Metformin Inhibits Glutaminase Activity and Protects against Hepatic Encephalopathy

AIM: To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ammonia production in vitro. METHODS: Eighty-two cirrhotic patients with type 2...

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Detalhes bibliográficos
Main Authors: Ampuero, Javier, Ranchal, Isidora, Nuñez, David, Díaz-Herrero, María del Mar, Maraver, Marta, del Campo, José Antonio, Rojas, Ángela, Camacho, Inés, Figueruela, Blanca, Bautista, Juan D., Romero-Gómez, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499552/
https://ncbi.nlm.nih.gov/pubmed/23166628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049279
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