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A Role for Dendritic mGluR5-Mediated Local Translation of Arc/Arg3.1 in MEF2-Dependent Synapse Elimination

Experience refines synaptic connectivity through neural activity-dependent regulation of transcription factors. Although activity-dependent regulation of transcription factors has been well described, it is unknown whether synaptic activity and local, dendritic regulation of the induced transcripts...

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Main Authors: Julia R. Wilkerson, Nien-Pei Tsai, Marina A. Maksimova, Hao Wu, Nicole P. Cabalo, Kristofer W. Loerwald, Jason B. Dictenberg, Jay R. Gibson, Kimberly M. Huber
格式: Artigo
語言:Inglês
出版: Elsevier 2014-06-01
叢編:Cell Reports
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211124714003374
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