Φορτώνει......
Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.
Monoubiquitylation of the homotrimeric DNA sliding clamp PCNA at lysine residue 164 (PCNA(K164)) is a highly conserved, DNA damage-inducible process that is mediated by the E2/E3 complex Rad6/Rad18. This ubiquitylation event recruits translesion synthesis (TLS) polymerases capable of replicating acr...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science (PLoS)
2011-01-01
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Σειρά: | PLoS ONE |
Διαθέσιμο Online: | http://europepmc.org/articles/PMC3031632?pdf=render |
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