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Megakaryocytes form linear podosomes devoid of digestive properties to remodel medullar matrix
Abstract Bone marrow megakaryocytes (MKs) undergo a maturation involving contacts with the microenvironment before extending proplatelets through sinusoids to deliver platelets in the bloodstream. We demonstrated that MKs assemble linear F-actin-enriched podosomes on collagen I fibers. Microscopy an...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2022-04-01
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| Colecção: | Scientific Reports |
| Acesso em linha: | https://doi.org/10.1038/s41598-022-10215-x |
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