TMED2 binding restricts SMO to the ER and Golgi compartments.

Hedgehog (HH) signaling is important for embryonic pattering and stem cell differentiation. The G protein-coupled receptor (GPCR) Smoothened (SMO) is the key HH signal transducer modulating both transcription-dependent and transcription-independent responses. We show that SMO protects naive mouse em...

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Xehetasun bibliografikoak
Egile Nagusiak: Giulio Di Minin, Markus Holzner, Alice Grison, Charles E Dumeau, Wesley Chan, Asun Monfort, Loydie A Jerome-Majewska, Henk Roelink, Anton Wutz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2022-03-01
Saila:PLoS Biology
Sarrera elektronikoa:https://doi.org/10.1371/journal.pbio.3001596
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