Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer

Clinical evidences have demonstrated limited efficacy of HER2-targeted therapies in patients with gastric cancer (GC). Here the authors show that survival benefit to anti-HER2 antibody Trastuzumab is reduced in GC patients with high levels of the caveolin-1 and that, in preclinical cancer models, an...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Patrícia M. R. Pereira, Komal Mandleywala, Sébastien Monette, Melissa Lumish, Kathryn M. Tully, Sandeep Surendra Panikar, Mike Cornejo, Audrey Mauguen, Ashwin Ragupathi, Nai C. Keltee, Marissa Mattar, Yelena Y. Janjigian, Jason S. Lewis
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2022-05-01
叢編:Nature Communications
在線閱讀:https://doi.org/10.1038/s41467-022-30142-9
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍