Mitochondrial DNA content of peripheral blood mononuclear cells in ART untreated & stavudine/zidovudine treated HIV-1-infected patients

Background & objectives: Nucleoside reverse transcriptase inhibitors (NRTIs) are known to cause mitochondrial toxicity. This study was done to estimate mitochondrial DNA (mtDNA) content of peripheral blood mononuclear cells (PBMCs) among human immunodeficiency virus (HIV) infected, NRTI treated...

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Главные авторы: Dhakshinamoorthy Subashini, Thongadi Ramesh Dinesha, Rao B Srirama, Jayaseelan Boobalan, Selvamuthu Poongulali, Devaraj A Chitra, Sarvode N Mothi, Sunil Suhas Solomon, Shanmugam Saravanan, Suniti Solomon, Pachamuthu Balakrishnan
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer Medknow Publications 2018-01-01
Серии:Indian Journal of Medical Research
Предметы:
ART naïve - HIV - mitochondrial dysfunction - mitochondrial DNA - nucleoside reverse transcriptase inhibitors - peripheral blood mononuclear cells - toxicity
Online-ссылка:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=148;issue=2;spage=207;epage=214;aulast=Subashini
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