Mitochondrial DNA content of peripheral blood mononuclear cells in ART untreated & stavudine/zidovudine treated HIV-1-infected patients

Background & objectives: Nucleoside reverse transcriptase inhibitors (NRTIs) are known to cause mitochondrial toxicity. This study was done to estimate mitochondrial DNA (mtDNA) content of peripheral blood mononuclear cells (PBMCs) among human immunodeficiency virus (HIV) infected, NRTI treated...

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Detalhes bibliográficos
Main Authors: Dhakshinamoorthy Subashini, Thongadi Ramesh Dinesha, Rao B Srirama, Jayaseelan Boobalan, Selvamuthu Poongulali, Devaraj A Chitra, Sarvode N Mothi, Sunil Suhas Solomon, Shanmugam Saravanan, Suniti Solomon, Pachamuthu Balakrishnan
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2018-01-01
Colecção:Indian Journal of Medical Research
Assuntos:
ART naïve - HIV - mitochondrial dysfunction - mitochondrial DNA - nucleoside reverse transcriptase inhibitors - peripheral blood mononuclear cells - toxicity
Acesso em linha:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=148;issue=2;spage=207;epage=214;aulast=Subashini
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