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Mechanisms of Disulfide Bond Formation in Nascent Polypeptides Entering the Secretory Pathway

Disulphide bonds are an abundant feature of proteins across all domains of life that are important for structure, stability, and function. In eukaryotic cells, a major site of disulphide bond formation is the endoplasmic reticulum (ER). How cysteines correctly pair during polypeptide folding to form...

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Main Authors: Philip J. Robinson, Neil J. Bulleid
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-08-01
叢編:Cells
主題:
PDI
ER
在線閱讀:https://www.mdpi.com/2073-4409/9/9/1994
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