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Mechanisms of Disulfide Bond Formation in Nascent Polypeptides Entering the Secretory Pathway

Disulphide bonds are an abundant feature of proteins across all domains of life that are important for structure, stability, and function. In eukaryotic cells, a major site of disulphide bond formation is the endoplasmic reticulum (ER). How cysteines correctly pair during polypeptide folding to form...

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Bibliografiske detaljer
Main Authors: Philip J. Robinson, Neil J. Bulleid
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-08-01
Serier:Cells
Fag:
PDI
ER
Online adgang:https://www.mdpi.com/2073-4409/9/9/1994
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