Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways.

Cdc25C is a cell cycle protein of the dual specificity phosphatase family essential for activating the cdk1/Cyclin B1 complex in cells entering into mitosis. Since altered cell cycle is a hallmark of human cancers, we investigated androgen regulation of Cdc25C protein in human prostate cancer (PCa)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yu-Wei Chou, Li Zhang, Sakthivel Muniyan, Humera Ahmad, Satyendra Kumar, Syed Mahfuzul Alam, Ming-Fong Lin
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2013-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC3630140?pdf=render
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