Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver

Development of a safe and effective method for gene delivery to hepatocytes is a critical step toward gene therapy for liver diseases. Here, we assessed the parameters for gene delivery to the livers of large animals (pigs, 40–65 kg) using an image-guided hydrodynamics-based procedure that involves...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kenya Kamimura, Takeshi Suda, Guisheng Zhang, Yutaka Aoyagi, Dexi Liu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2013-01-01
Serie:Molecular Therapy: Nucleic Acids
Ämnen:
gene therapy
human α-1 antitrypsin
hydrodynamic gene delivery
image-guided gene delivery
non-viral vector
Länkar:http://www.sciencedirect.com/science/article/pii/S2162253116301846
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk