Osthole inhibits triple negative breast cancer cells by suppressing STAT3

Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subgroup of human breast cancer. Patients with TNBC have poor clinical outcome as they are non-responsive to current targeted therapies. There is an urgent need to identify new therapeutic targets and develop more effective tr...

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Hlavní autoři: Xuanxuan Dai, Changtian Yin, Yi Zhang, Guilong Guo, Chengguang Zhao, Ouchen Wang, Youqun Xiang, Xiaohua Zhang, Guang Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-12-01
Edice:Journal of Experimental & Clinical Cancer Research
Témata:
Osthole
STAT3
Triple-negative breast cancer
Cell apoptosis
Xenografts
On-line přístup:http://link.springer.com/article/10.1186/s13046-018-0992-z
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