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Ixazomib Improves Bone Remodeling and Counteracts Sonic Hedgehog Signaling Inhibition Mediated by Myeloma Cells

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by an accumulation of plasma cells (PC) in the bone marrow (BM), leading to bone loss and BM failure. Osteolytic bone disease is a common manifestation observed in MM patients and represents the most severe cause of morbidity, leading...

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書誌詳細
主要な著者: Daniele Tibullo, Anna Longo, Nunzio Vicario, Alessandra Romano, Alessandro Barbato, Michelino Di Rosa, Ignazio Barbagallo, Carmelina Daniela Anfuso, Gabriella Lupo, Rosario Gulino, Rosalba Parenti, Giovanni Li Volti, Giuseppe Alberto Palumbo, Francesco Di Raimondo, Cesarina Giallongo
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2020-01-01
シリーズ:Cancers
主題:
オンライン・アクセス:https://www.mdpi.com/2072-6694/12/2/323
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