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Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model

Abstract Background Microglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promotes macrophage differentiation toward the M2 anti-inf...

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Autores principales: Yi-Ling Liu, Wei-Ting Chen, Yu-Yi Lin, Po-Hung Lu, Shie-Liang Hsieh, Irene Han-Juo Cheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2017-04-01
Colección:Molecular Neurodegeneration
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Acceso en línea:http://link.springer.com/article/10.1186/s13024-017-0173-0
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