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Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model
Abstract Background Microglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promotes macrophage differentiation toward the M2 anti-inf...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2017-04-01
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| Colecção: | Molecular Neurodegeneration |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13024-017-0173-0 |
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