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Rapid and Scalable Plant-Based Production of a Potent Plasmin Inhibitor Peptide

The backbone cyclic and disulfide bridged sunflower trypsin inhibitor-1 (SFTI-1) peptide is a proven effective scaffold for a range of peptide therapeutics. For production at laboratory scale, solid phase peptide synthesis techniques are widely used, but these synthetic approaches are costly and env...

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Main Authors: Mark A. Jackson, Kuok Yap, Aaron G. Poth, Edward K. Gilding, Joakim E. Swedberg, Simon Poon, Haiou Qu, Thomas Durek, Karen Harris, Marilyn A. Anderson, David J. Craik
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-05-01
Colecção:Frontiers in Plant Science
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fpls.2019.00602/full
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