Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

Abstract Background Defining the mechanisms that establish and regulate the transmission of epigenetic information from parent to offspring is critical for understanding disease heredity. Currently, the molecular pathways that regulate epigenetic information in the germline and its transmission to o...

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Detaylı Bibliyografya
Asıl Yazarlar: Jessica M. Stringer, Samuel C. Forster, Zhipeng Qu, Lexie Prokopuk, Moira K. O’Bryan, David K. Gardner, Stefan J. White, David Adelson, Patrick S. Western
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2018-09-01
Seri Bilgileri:BMC Biology
Konular:
Germline
Epigenetic reprogramming
PRC2
H3K27me3
Paternal inheritance
Fertility
Online Erişim:http://link.springer.com/article/10.1186/s12915-018-0569-5
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