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Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

Abstract Background Defining the mechanisms that establish and regulate the transmission of epigenetic information from parent to offspring is critical for understanding disease heredity. Currently, the molecular pathways that regulate epigenetic information in the germline and its transmission to o...

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Main Authors: Jessica M. Stringer, Samuel C. Forster, Zhipeng Qu, Lexie Prokopuk, Moira K. O’Bryan, David K. Gardner, Stefan J. White, David Adelson, Patrick S. Western
格式: Artigo
語言:Inglês
出版: BMC 2018-09-01
叢編:BMC Biology
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在線閱讀:http://link.springer.com/article/10.1186/s12915-018-0569-5
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