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Pharmacology of new oral anticoagulants: mechanism of action, pharmacokinetics, pharmacodynamics

Due to their mechanism of action, the new oral anticoagulants are named direct oral anticoagulants (DOACs). Dabigatran is a selective, competitive, direct inhibitor of thrombin (Factor IIa) while rivaroxaban, apixaban and edoxaban act by directly inhibiting the activated Factor X (FXa) in a selectiv...

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Bibliografski detalji
Glavni autori: Luca Masotti, Mauro Campanini
Format: Artigo
Jezik:Inglês
Izdano: PAGEPress Publications 2013-12-01
Serija:Italian Journal of Medicine
Teme:
Online pristup:http://www.italjmed.org/index.php/ijm/article/view/175
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