Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation in Vivo and in Vitro

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases characterized with a gradual loss of midbrain substantia nigra (SN) dopamine (DA) neurons. An excessive evidence demonstrated that microglia-mediated inflammation might be involved in the pathogenesis of PD. Thus, inhibiti...

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Detalhes bibliográficos
Main Authors: Guo-Qing Wang, Dai-Di Li, Chun Huang, Di-Sheng Lu, Chao Zhang, Shao-Yu Zhou, Jie Liu, Feng Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-01-01
Colecção:Frontiers in Molecular Neuroscience
Assuntos:
Parkinson’s disease
microglia
neuroinflammation
icariin
neuroprotection
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00441/full
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