Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization

Uveitis causes blindness and critical visual impairment in people of all ages, and retinal microglia participate in uveitis progression. Unfortunately, effective treatment is deficient. Icariin (ICA) is a bioactive monomer derived from Epimedium. However, the role of ICA in uveitis remains elusive....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Guoqing Wang, Xingran Li, Na Li, Xiaotang Wang, Siyuan He, Wanqian Li, Wei Fan, Ruonan Li, Jiangyi Liu, Shengping Hou
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2022-06-01
Sarja:Redox Biology
Aiheet:
Icariin
Uveitis
PRDX3
Microglia
M1 phenotype
M2 phenotype
Linkit:http://www.sciencedirect.com/science/article/pii/S2213231722000696
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