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Expression of Msx-1 is suppressed in bisphosphonate associated osteonecrosis related jaw tissue-etiopathology considerations respecting jaw developmental biology-related unique features

<p>Abstract</p> <p>Background</p> <p>Bone-destructive disease treatments include bisphosphonates and antibodies against the osteoclast differentiator, RANKL (aRANKL); however, osteonecrosis of the jaw (ONJ) is a frequent side-effect. Current models fail to explain the r...

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Detalhes bibliográficos
Main Authors: Schlegel Karl A, Nkenke Emeka, Stockmann Phillip, Ries Jutta, Hyckel Peter, Wehrhan Falk, Neukam Friedrich W, Amann Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2010-10-01
Colecção:Journal of Translational Medicine
Acesso em linha:http://www.translational-medicine.com/content/8/1/96
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