Isoform‐specific effects of transcription factor TCFL5 on the pluripotency‐related genes SOX2 and KLF4 in colorectal cancer development

Colorectal cancer (CRC) is a very common life‐threatening malignancy. Transcription factor‐like 5 (TCFL5) has been suggested to be involved in CRC. Here, we describe the expression of four alternative transcripts of TCFL5 and their relevance in CRC. Complete deletion of all isoforms drastically decr...

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Main Authors: Javier Galán‐Martínez, Konstantinos Stamatakis, Inés Sánchez‐Gómez, Silvia Vázquez‐Cuesta, Núria Gironés, Manuel Fresno
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2022-05-01
Series:Molecular Oncology
Assuntos:
colorectal cancer
isoforms
KLF4
SOX2
TCFL5
Acceso en liña:https://doi.org/10.1002/1878-0261.13085
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