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A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.

Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interlinked transcriptional and signaling networks control the fate of these cells towards maintenance of pluripotency or differentiation. In this study we hav...

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書誌詳細
主要な著者: Shen-Hsi Yang, Tuzer Kalkan, Claire Morrisroe, Austin Smith, Andrew D Sharrocks
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2012-01-01
シリーズ:PLoS Genetics
オンライン・アクセス:http://europepmc.org/articles/PMC3521700?pdf=render
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