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In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into understanding and minimising the excruciating effect...

Deskribapen osoa

Gorde:
Egile Nagusiak: Sharoen Yu Ming Lim, Jason Siau Ee Loo, Mustafa Alshagga, Mohammed Abdullah Alshawsh, Chin Eng Ong, Yan Pan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2022-01-01
Saila:Toxicology Reports
Gaiak:
Cathinone
CYP450
in vitro
in silico
Docking
Herb-drug interaction
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2214750022000695
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