In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5

Cathinone is the psychostimulatory major active ingredient of khat (Catha edulis Forsk) and are often co-abused with alcohols and polydrugs. With the increased consumption of khat and cathinones on a global scale, efforts should be channelled into understanding and minimising the excruciating effect...

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Autors principals:	Sharoen Yu Ming Lim, Jason Siau Ee Loo, Mustafa Alshagga, Mohammed Abdullah Alshawsh, Chin Eng Ong, Yan Pan
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-01-01
Col·lecció:	Toxicology Reports
Matèries:	Cathinone CYP450 in vitro in silico Docking Herb-drug interaction
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2214750022000695
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