Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141+ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8+ T Cell Response in Human Immune System Mice

Active co-delivery of tumor antigens (Ag) and α-galactosylceramide (α-GalCer), a potent agonist for invariant Natural Killer T (iNKT) cells, to cross-priming CD8α+ dendritic cells (DCs) was previously shown to promote strong anti-tumor responses in mice. Here, we designed a nanoparticle-based vaccin...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Jing Huang, Jing Zhou, Reem Ghinnagow, Toshiyuki Seki, Sho Iketani, Daphnée Soulard, Patrick Paczkowski, Yukiko Tsuji, Sean MacKay, Luis Javier Cruz, François Trottein, Moriya Tsuji
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2020-08-01
Ráidu:	Frontiers in Immunology
Fáttát:	nanovaccine targeting human CD141+ DCs iNKT cells α-galactosylceramide CD8+ T cells
Liŋkkat:	https://www.frontiersin.org/article/10.3389/fimmu.2020.02043/full
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!