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PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses

Tumor-specific neoantigens can be highly immunogenic, but their identification for each patient and the production of personalized cancer vaccines can be time-consuming and prohibitively expensive. In contrast, tumor-associated antigens are widely expressed and suitable as an off the shelf immunothe...

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Principais autores: Yusuf Dölen, Uzi Gileadi, Ji-Li Chen, Michael Valente, Jeroen H. A. Creemers, Eric A. W. Van Dinther, N. Koen van Riessen, Eliezer Jäger, Martin Hruby, Vincenzo Cerundolo, Mustafa Diken, Carl G. Figdor, I. Jolanda M. de Vries
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-02-01
Serier:Frontiers in Immunology
Fag:
NY-ESO-1
iNKT cell
B cell epitope
peptide vaccine
IMM60
PLGA nanoparticle
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.641703/full
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